Section Ii: B the Effect of Soy Protein on Homocysteine
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چکیده
In 1999 FDA approved a soy/heart health claim on the premise that soy protein lowers total and LDL cholesterol. The FDA gave no consideration to soy protein's effect on other cardiovascular risk factors. A considerable body evidence suggests that homocysteine level is a far better marker of heart disease risk than cholesterol.1-5 We submit that it is improper for FDA is to allow a claim for soy protein being heart healthy unless it also has shown a consistent and significant effect on the lowering of homocysteine levels. No such effect has been found.
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Lipid-lowering effect of 2 dosages of a soy protein supplement in hypercholesterolemia.
The lipid-lowering effect of a soy-based protein supplement was evaluated in an 8-week randomized, placebo-controlled trial in patients with hypercholesterolemia. A total of 117 patients (63 men and 54 women) received soy protein, either 15 or 25 g/d or placebo. In the active treatment groups low-density lipoprotein cholesterol levels decreased significantly by 5.9% and 1.1% respectively, but i...
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